The alkali salt acts as a base catalyst and other bases can be used instead.
Erlenmeyer determine the Azalactone structure of the Introduction product Equation 4 and extended the scope of Perkin reaction to other aldehydes Erlenmeyer Azalactone synthesis . Synth Coll 1: When 2, 6-dimethoxy-p-bezoquinone treated with 1. Equation 8 According to Ahramjian and Zimmerman, the condensation between the aromatic aldehyde and phenylacetic acid is not reversible . On the other hand, 2-pyridinecarbaldehyde do not give Perkin product 3- -pyridyl acrylic acid  but it gives the mixture of Equation 12 indolizine derivatives equation 10 . H propionic anhydride in presence of sodium propionate gives a mixture 2. Heteroaromatic aldehydes such as furfural  equation 1 and 2-thiophenecarbaldehyde  also take part in this reaction. Sixth Edition. Pohjala E Indolizine Derivatives. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Ruggli P, Staub A m-phenylene diacrylate. Heterocycles
Because of increased hindrance of side chain higher aldehydes and cis-citral the reactivity of Equation 9 carbonyl group decreases and inally do not afords Perkin product. Some Support for this mechanism comes from fact that anhydrides with only 1 alpha hydrogen donot give this reaction.
Eur J Org Chem 4. Pohjala E Indolizine Derivatives.
J Am Chem Soc Scand Synthesis Generally, such type of reaction is only applicable to aromatic aldehyde and useful for the preparation of substituted cinnamic acid Equation 3 .
Erlenmeyer determine the Azalactone structure of the Introduction product Equation 4 and extended the scope of Perkin reaction to other aldehydes Erlenmeyer Azalactone synthesis . Li JJ Name Reaction.
Azalactone It is type of condensation reaction, which involve the condensation or oxazolone acts as important intermediate for the synthesis of - of acidic anhydride and aldehyde in the presence of weak base i.
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